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This review aims to summarize advances in mesenchymal stem cell-based therapies for skin repair and rejuvenation.

July 1, 2026Discover Immunity.Open Access

Mesenchymal stem cell therapy for skin repair and rejuvenation

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Narrative review summarizes mesenchymal stem cell strategies for skin repair and rejuvenation, suggesting new treatment opportunities.

This review aims to summarize advances in mesenchymal stem cell-based therapies for skin repair and rejuvenation.
Review of literature on mesenchymal stem cell applications in skin repair and rejuvenation
Discussion on various delivery strategies, including direct therapy and use of extracellular vesicles
Analysis of differences between neonatal and adult-derived stem cells
Mesenchymal stem cells exhibit promising potential for treating chronic wounds and promoting skin rejuvenation.
Neonatal sources of mesenchymal stem cells show advantages in cell availability and immunomodulatory activity.
Different delivery strategies have functional distinctions that impact their therapeutic outcomes.

Raitman et al. (2026) studied this question.

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