What is the clinical evidence from this study?

Study design: Case Report. Population: Severe anemia and congestive heart failure (n=1). Intervention: Severe anemia.

What does this research mean for the field?

Severe anemia can present as high-output congestive heart failure with preserved ejection fraction and pulmonary congestion. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This case examines the unusual presentation of severe anemia leading to heart failure with preserved ejection fraction.

July 1, 2026Open Access

Severe Anemia Presenting as Heart Failure With Preserved Ejection Fraction

View Full Paper

Ask AI

Bookmark

Key result

Severe anemia presents as high-output HFpEF with pulmonary congestion in a teenage male.

Why the study?

Patients with chronic severe anemia and no cardiovascular disease rarely develop congestive heart failure symptoms, and severe anemia can induce hyperdynamic circulation and volume overload affecting echocardiographic parameters.

Population

A 16-year-old male patient with severe anemia and congestive heart failure

Design

Case report

Authors

AKAkhil Mehrotra*, Saadia Salamat, Mohammed Shaban, Anjali Kumari

Discussion

Member takes

Implication

Consider anemia in adolescent HFpEF; extends echocardiographic observations but leaves causal role hypothesis-generating.

Key Points

This case examines the unusual presentation of severe anemia leading to heart failure with preserved ejection fraction.
Clinical examination and various diagnostic tests, including ECG and echocardiographic investigations.
Assessment of global left ventricular strain using two-dimensional echocardiography.
The patient displayed significant pulmonary congestion due to severe anemia.
Echocardiographic studies indicated alterations in left ventricular function and strain parameters.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 16-year-old male patient with severe anemia who developed congestive heart failure.

Exposure

Clinical examination, pathological, radiological, ECG, and two-dimensional echocardiographic investigations (including 2D strain imaging and global longitudinal strain)

Outcome

Assessment of left ventricular dysfunction using 2D strain imaging and global longitudinal strain via echocardiographysurrogate

Severe anemia can present as high output heart failure with preserved ejection fraction, with significant alterations detectable via 2D strain echocardiography.

Cite This Study

Akhil Mehrotra*, Saadia Salamat, Mohammed Shaban, Anjali Kumari (2026) conducted a case report in Severe anemia and congestive heart failure (n=1). Severe anemia was evaluated. Severe anemia in a 16-year-old male patient presented as high output congestive heart failure with preserved ejection fraction and pulmonary congestion.

synapsesocial.com/papers/6a44aeba5cd2549c8bc43d99 https://doi.org/10.5281/zenodo.21026880

View Full Paper

Ask AI

Bookmark

Severe Anemia Presenting as Heart Failure With Preserved Ejection Fraction

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Severe Anemia Presenting as Heart Failure With Preserved Ejection Fraction

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider