Key result
GLS via STE detects subtle cardiac changes in a teen with severe anemia and HFpEF.
Why the study?
Severe anemia can cause cardiac alterations with a subtle boundary between overt and asymptomatic dysfunction, making advanced imaging essential to detect early subtle cardiac changes.
Design
Case report
Authors
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May support GLS via STE for early dysfunction detection in anemic HFpEF; hypothesis-generating, leaves open prospective validation.
Case Report (n=1)
Speckle tracking echocardiography may serve as a practical, non-invasive tool for assessing global longitudinal strain to detect early silent myocardial dysfunction in patients with severe anemia.
Mehrotra et al. (2026) conducted a case report in Severe anemia complicated by heart failure with preserved ejection fraction (HFpEF) (n=1). Global longitudinal strain (GLS) analysis via speckle tracking echocardiography (STE) was evaluated. Global longitudinal strain analysis via speckle tracking echocardiography was utilized to evaluate subtle cardiac changes in a teenage male with severe anemia complicated by HFpEF.
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