June 30, 2005Monaldi Archives for Chest DiseaseOpen Access

Anemia in chronic heart failure patients: comparison between invasive and non-invasive prognostic markers

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Why the study?

Does anemia predict cardiac death or urgent heart transplantation in patients with chronic heart failure?

Population

980 consecutive patients with chronic heart failure, mean age 53, 85% male, LVEF 25%, 45% NYHA class III-IV…

Comparison

Anemia vs Non-anemic patients (hemoglobin ≥ 12 g/dl)

Design

Cohort

Follow-up

3 years

Authors

MCMonica CeresaIstituti Clinici Scientifici Maugeri SCSoccorso CapomollaOspedale di Circolo e Fondazione Macchi GPGian Domenico PinnaHeart Failure & Transplant

Discussion

Member takes

Implication

Anemia may aid noninvasive risk stratification in chronic HF; leaves open whether incorporating it improves outcomes or warrants prospective validation.

Structured PICO

Does anemia predict cardiac death or urgent heart transplantation in patients with chronic heart failure?

Population

980 consecutive patients with chronic heart failure (ischemic, idiopathic dilated cardiomyopathy, or other), mean age 53, 85% male, LVEF 25%, 45% NYHA class III-IV, admitted to a heart failure unit for evaluation and treatment of advanced heart failure.

Intervention

Anemia (defined as hemoglobin concentration < 12 g/dl)

Comparator

Non-anemic patients (hemoglobin ≥ 12 g/dl)

Outcome

Cardiac death or urgent heart transplantation at 3-year follow-uphard clinical

Anemia is an independent predictor of mortality and urgent transplantation in chronic heart failure, offering similar prognostic accuracy to more complex invasive or cardiopulmonary exercise testing parameters.

Limitations

Selected patients entering a heart transplantation program
Elderly patients, those with diastolic heart failure, and women were under-represented
Etiology of the anemia was not studied
Iatrogenic causes of anemia and possible therapeutic treatments undertaken were not considered

Cite This Study

Ceresa et al. (2005) studied this question.

synapsesocial.com/papers/6a73a7d30bc450a817279fc8 https://doi.org/10.4081/monaldi.2005.598

Topics

Heart transplantation Heart failure HFrEF treatment Heart failure hospitalization HFpEF management

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Implication

Anemia may aid noninvasive risk stratification in chronic HF; leaves open whether incorporating it improves outcomes or warrants prospective validation.

Anemia in chronic heart failure patients: comparison between invasive and non-invasive prognostic markers

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Topics

Anemia in chronic heart failure patients: comparison between invasive and non-invasive prognostic markers

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Topics

Also Consider