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July 1, 2026Tropical Medicine and HealthOpen Access

Epidemiological, virological, and clinical characteristics of dengue in the Lao People’s Democratic Republic, 2022–2023: a cross-sectional study

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Authors

DXDalouny XayavongVSVirasack SomoulayBKBouaphanh Khamphaphongphane

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Overview

Cross-sectional study investigates dengue characteristics in Lao PDR, revealing factors linked to severity.

Key Points

  • This study aims to explore the epidemiology, clinical features, and factors linked to severe dengue in Lao PDR.
  • Cross-sectional study utilizing serum samples from the National Dengue Surveillance System (2022-2023).
  • Serum samples tested for DENV detection and serotyping via reverse-transcription PCR and ELISAs.
  • Multinomial logistic regression analyzed factors associated with disease severity.
  • 615 out of 1098 serum samples tested DENV-positive, with significant regional differences in serotype distribution (p < 0.0001).
  • DENV-2 infection was linked to higher severity (83.3%), primarily in secondary infections (OR = 2.38, 95% CI: 0.84-6.74).
  • Severe dengue notably more likely in the southern (OR = 11.16, 95% CI: 3.05-40.77) and central regions (OR = 10.34, 95% CI: 2.81-38.09).

Cite This Study

Xayavong et al. (2026) studied this question.

synapsesocial.com/papers/6a44af635cd2549c8bc44532https://doi.org/10.1186/s41182-026-01008-3
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Also Consider

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  1. 1Bayesian spatio-temporal analysis of dengue transmission in Lao PDR2024 · 5 citations
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