Key result
Ultra-marathon running linked to mild reductions in LV and RV global strains within normal limits.
Why the study?
The impact of ultra-endurance exercise on global and segmental longitudinal deformation of all cardiac chambers and on inter-chamber functional relationships had not been thoroughly investigated.
Does running a 246 km ultra-marathon alter global and segmental longitudinal deformation of cardiac chambers in athletes?
Population
27 athletes finishing a 246 Km ultra-marathon out of 60 screened
Comparison
Post-race at the finish line vs pre-race baseline echocardiographic assessment
Design
Observational cohort study
Authors
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Preserved apical strain after ultra-marathon suggests no acute clinical concern; leaves open long-term prognostic implications for athletes.
Observational (n=27)
Does running a 246 km ultra-marathon alter global and segmental longitudinal deformation of cardiac chambers in athletes?
Absolute Event Rate: -18.8% vs -20.9%
p-value: p=0.009
Running a 246 km ultra-marathon causes subtle decreases in LV and RV global strain that mostly remain within normal limits, largely due to preserved apical deformation.
Pagourelias et al. (2020) conducted an observational in Healthy ultra-marathon runners (n=27). 246 km ultra-marathon race vs. Pre-race baseline was evaluated on Left ventricular (LV) global strain (p=0.009). Running a 246 km ultra-marathon decreased left ventricular (-20.9% to -18.8%, p=0.009) and right ventricular (-22.9% to -21.2%, p=0.04) global strains, though values remained within normal range.
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