Key result
Current smoking was associated with an increased risk of all-cause cardiovascular disease compared with never smoking (HR 1.7; 95% CI 1.3-2.2).
Why the study?
Does current smoking increase the risk of cardiovascular disease and CHD events in a multiethnic cohort free of baseline cardiovascular disease?
Cohort (n=6,814)
Yes
Does current smoking increase the risk of cardiovascular disease and CHD events in a multiethnic cohort free of baseline cardiovascular disease?
Hazard Ratio: 1.7 (95% CI 1.3–2.2)
Current smoking remains a significant modifiable risk factor for cardiovascular events, with risk further stratified by coronary artery calcium and high-sensitivity C-reactive protein levels.
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Smoking cessation may warrant emphasis in primary prevention; extends observational links between CAC, inflammation, and events but leaves causality open.
McEvoy et al. (2015) conducted a cohort in Free of cardiovascular disease and coronary heart disease (n=6,814). Current smoking vs. Never smokers was evaluated on All-cause cardiovascular disease (HR 1.7, 95% CI 1.3-2.2). Current smoking was associated with an increased risk of all-cause cardiovascular disease compared with never smoking (HR 1.7; 95% CI 1.3-2.2).
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