Key result
Elevated depression symptoms in patients with implantable cardioverter defibrillators were associated with significantly lower heart rate variability (RMSSD 15.25 vs 24.97 ms; p=0.002).
Why the study?
Are symptoms of depression and anxiety associated with reduced heart rate variability in patients with implantable cardioverter defibrillators?
Population
44 patients with an implantable cardioverter defibrillator (ICD), mean age 62.1 +/- 9.3 years
Comparison
Elevated depression symptoms or high anxiety… vs Low depression symptoms or low anxiety levels
Design
Cross-sectional
Authors
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May warrant mood screening in ICD patients; leaves open effects on arrhythmias or survival.
Cross-Sectional (n=44)
Are symptoms of depression and anxiety associated with reduced heart rate variability in patients with implantable cardioverter defibrillators?
Absolute Event Rate: 15.25% vs 24.97%
p-value: p=.002
Elevated depression and anxiety symptoms in ICD patients are associated with reduced parasympathetic control as measured by heart rate variability, which may contribute to arrhythmic risk.
Francis et al. (2009) conducted a cross-sectional in Implantable cardioverter defibrillator (ICD) (n=44). Elevated depression symptoms vs. Low depression symptoms was evaluated on Heart rate variability (RMSSD) (p=.002). Elevated depression symptoms in patients with implantable cardioverter defibrillators were associated with significantly lower heart rate variability (RMSSD 15.25 vs 24.97 ms; p=0.002).
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