Key result
High plasma trimethylamine-N-oxide (TMAO) levels are independently associated with mild cognitive impairment in an elderly population with high cardiovascular risk (p=0.046).
Why the study?
Are high plasma TMAO levels associated with mild cognitive impairment in a high cardiovascular risk elderly population?
Are high plasma TMAO levels associated with mild cognitive impairment in a high cardiovascular risk elderly population?
Plasma TMAO levels may serve as an independent risk factor for mild cognitive impairment in elderly patients with high cardiovascular risk.
Should not yet guide MCI screening or management; leaves open causality and need for prospective validation in high-CV-risk elderly.
0.046), when adjusted for age, gender, health care service scheme, smoking history, metabolic syndrome, and history of established CV events. The high TMAO level was associated with MCI, after adjustment for potential confounding factors. These findings demonstrate that plasma TMAO levels can serve for target prediction as an independent risk factor for MCI in this population.
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Buawangpong et al. (2022) studied this question. High plasma trimethylamine-N-oxide (TMAO) levels are independently associated with mild cognitive impairment in an elderly population with high cardiovascular risk (p=0.046).
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