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Evaluate the neurologic complications associated with current and emerging CAR-T cell therapies.

July 2, 2026NeurotherapeuticsOpen Access

Neurological complications of current and emerging CAR-T cell therapies

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Evaluate the neurologic complications associated with current and emerging CAR-T cell therapies.
Reviewed existing literature on CAR-T therapies focusing on neurological complications.
Summarized acute and long-term neurologic toxicity findings.
Discussed potential interventions to mitigate these toxicities.
Identified high frequency of neurologic complications in CAR-T therapies.
Highlighted the need for monitoring and managing neurotoxicities in clinical settings.
Discussed the implications of utilizing CAR-T therapies for solid tumors and autoimmune conditions.

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Overview assesses neurologic complications in CAR-T therapies for hematologic and solid tumors, suggesting necessary interventions.

Hauswirth et al. (2026) studied this question.

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