Key result
Diabetic patients had more painless ST depression on exercise testing than non-diabetics (69% vs 35%, p<0.001), which was strongly associated with severe autonomic neuropathy (92% vs 39%, p<0.01).
Why the study?
Is silent myocardial ischemia during exercise testing more common in diabetic patients, and is it associated with autonomic dysfunction?
Population
1,653 patients undergoing exercise testing and 30 diabetic patients with known or suspected coronary artery…
Design
Cohort
Authors
Loading...
May warrant autonomic neuropathy screening in diabetics before exercise testing; leaves open whether this improves risk stratification or outcomes.
Observational (n=1,653)
No
Is silent myocardial ischemia during exercise testing more common in diabetic patients, and is it associated with autonomic dysfunction?
Absolute Event Rate: 69% vs 35%
p-value: p=<0.001
Silent myocardial ischemia is significantly more common in diabetic patients during exercise testing and is strongly associated with the presence of severe autonomic neuropathy.
Murray et al. (1990) conducted an observational in Diabetes Mellitus with known or suspected coronary artery disease (n=1,653). Diabetes mellitus vs. Non-diabetic patients was evaluated on Painless ST depression on positive exercise testing (p=<0.001). Diabetic patients had more painless ST depression on exercise testing than non-diabetics (69% vs 35%, p<0.001), which was strongly associated with severe autonomic neuropathy (92% vs 39%, p<0.01).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: