Key result
Following left ventricular reconstruction, inward displacement of basal and mid-cavity left ventricular segments increased by 27% (p<0.001) and 37% (p<0.001), respectively.
Why the study?
Pre- and post-procedural regional functional left ventricular assessment with current imaging techniques remains limited in ischemic HFrEF patients undergoing left ventricular reconstruction.
Does left ventricular reconstruction with the Revivent System improve regional left ventricular function as measured by inward displacement in patients with ischemic HFrEF?
Population
36 ischemic HFrEF patients undergoing left ventricular reconstruction with the Revivent System
Comparison
Pre-procedural vs post-procedural inward displacement, and comparison with speckle tracking echocardiographic strain
Design
Observational imaging study
Authors
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Supports regional LV function gains after reconstruction in ischemic HFrEF; leaves open need for randomized outcome trials.
Observational (n=36)
Does left ventricular reconstruction with the Revivent System improve regional left ventricular function as measured by inward displacement in patients with ischemic HFrEF?
Effect estimate: 27% and 37% increase
p-value: p=<0.001
Inward displacement is a promising novel imaging method that correlates with echocardiographic strain and demonstrates significant improvements in basal and mid-cavity LV contractility following left ventricular reconstruction in ischemic HFrEF.
Hegeman et al. (2023) conducted an observational in Ischemic heart failure with reduced ejection fraction (HFrEF) (n=36). Left ventricular reconstruction with the Revivent System vs. Pre-procedural baseline was evaluated on Inward displacement of basal and mid-cavity left ventricular segments (27% and 37% increase, p=<0.001). Following left ventricular reconstruction, inward displacement of basal and mid-cavity left ventricular segments increased by 27% (p<0.001) and 37% (p<0.001), respectively.
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