Key result
Echo-derived hemodynamic force analysis detects subclinical mechanical abnormalities using routine transthoracic imaging.
Why the study?
A new mathematical model allows derivation of hemodynamic force parameters from routine transthoracic echocardiography, but the theoretical background, physiological patterns, and pathological alterations need illustration.
HDF analysis derived from standard echocardiography may provide a more sensitive evaluation of ventricular mechanics and dyssynchrony than conventional imaging.
May enable earlier detection of subclinical LV dysfunction on routine echocardiography; leaves open prospective validation before clinical adoption.
Hemodynamic force (HDF) analysis represents a novel approach to quantify intraventricular pressure gradients, responsible for blood flow. A new mathematical model allows the derivation of HDF parameters from routine transthoracic echocardiography, making this tool more accessible for clinical use. HDF analysis is considered the fluid dynamics correlate of deformation imaging and may be even more sensitive to detect mechanical abnormalities. This has the potential to add incremental clinical value, allowing earlier detection of pathology or immediate evaluation of response to treatment. In this article, the theoretical background and physiological patterns of HDF in the left ventricle are provided. In pathological situations, the HDF pattern might alter, which is illustrated with a case of ST segment elevation myocardial infarction and non-ischemic cardiomyopathy with typical left bundle branch block.
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Laenens et al. (2022) conducted a review in Cardiac dysfunction. Hemodynamic force (HDF) analysis by echocardiography was evaluated. A new mathematical model allows the derivation of hemodynamic force parameters from routine transthoracic echocardiography to detect subclinical mechanical abnormalities.
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