Key result
The intra-individual variability of the pre-ejection period at rest is small, with no significant difference in mean pre-ejection period between healthy volunteers and those with cardiovascular risk factors (p=0.236).
Why the study?
Does the intra-individual variability of the pre-ejection period justify the use of pulse transit time as an approximation of vascular transit time?
Population
60 volunteers divided into three groups of 20: 1) control without cardiovascular disease aged <50 years, 2)…
Design
Cross-sectional
Authors
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Supports PTT as stable approximation of vascular transit time within individuals; hypothesis-generating for arterial stiffness monitoring.
Observational (n=60)
No
Does the intra-individual variability of the pre-ejection period justify the use of pulse transit time as an approximation of vascular transit time?
Absolute Event Rate: 57.6% vs 58.5%
p-value: p=0.236
The small intra-individual variability of the pre-ejection period indicates that pulse transit time is a reliable, non-invasive approximation of vascular transit time for monitoring arterial stiffness.
Kortekaas et al. (2018) conducted an observational in Healthy volunteers and individuals with cardiovascular risk factors (n=60). Cardiovascular risk factors and age >50 years vs. Healthy volunteers aged <50 years was evaluated on Mean pre-ejection period (PEP) at rest (p=0.236). The intra-individual variability of the pre-ejection period at rest is small, with no significant difference in mean pre-ejection period between healthy volunteers and those with cardiovascular risk factors (p=0.236).
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