Key result
PPG-PTT correlated well with blood pressure levels (R2 0.81-0.85), similar to invasive PTT, while PAT had significantly lower correlation (R2 0.70, P<0.005 vs I-PTT).
Population
Swine model during baseline conditions and infusions of various hemodynamic drugs
Comparison
Noninvasive pulse transit time estimates vs Invasive pulse transit time (I-PTT)
Design
Preclinical
Authors
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PPG-PTT merits further preclinical testing for cuffless BP; leaves open human translation and validation.
p-value: p=<0.005
PPG-PTT is superior to PAT and comparable to invasive PTT as a marker of blood pressure, suggesting its potential utility for cuff-less blood pressure monitoring.
Gao et al. (2016) studied Blood pressure monitoring. Noninvasive pulse transit time estimates (PPG-PTT and PAT) vs. Invasive pulse transit time (I-PTT) was evaluated on Correlation (R2) with blood pressure levels (p=<0.005). PPG-PTT correlated well with blood pressure levels (R2 0.81-0.85), similar to invasive PTT, while PAT had significantly lower correlation (R2 0.70, P<0.005 vs I-PTT).
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