What is the clinical evidence from this study?

Study design: Observational. Population: Healthy (n=22). Intervention: Weighing scale-based pulse transit time (Scale PTT) vs. Conventional pulse arrival time (PAT). Primary outcome: Tracking of diastolic blood pressure changes (correlation coefficient) (Correlation coefficient -0.80, p=<0.05).

December 15, 2016Scientific ReportsOpen Access

Weighing Scale-Based Pulse Transit Time is a Superior Marker of Blood Pressure than Conventional Pulse Arrival Time

Q: What are the key findings of this study?

Weighing scale-based pulse transit time tracked diastolic blood pressure changes significantly better than conventional pulse arrival time (correlation coefficient -0.80 vs -0.60).

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Key result

Weighing scale-based pulse transit time tracked diastolic blood pressure changes significantly better than conventional pulse arrival time (correlation coefficient -0.80 vs -0.60).

Why the study?

Does scale-based pulse transit time improve the tracking of blood pressure changes compared to conventional pulse arrival time in humans?

Study Design

Type

Observational (n=22)

Multicenter

Yes

Structured PICO

Does scale-based pulse transit time improve the tracking of blood pressure changes compared to conventional pulse arrival time in humans?

Population

22 young, healthy adults (mean age 25, 14% female) who underwent hemodynamic interventions to evaluate non-invasive blood pressure tracking.

Intervention

Scale pulse transit time (PTT) measured via a bathroom weighing scale-like system using ballistocardiography and foot photoplethysmography (PPG) waveforms

Comparator

Conventional pulse arrival time (PAT) measured via time delay between ECG and finger PPG waveforms

Outcome

Tracking of diastolic and systolic blood pressure changes compared to cuff blood pressuresurrogate

Main Result

Effect estimate: Correlation coefficient -0.80

Absolute Event Rate: -0.8% vs -0.6%

p-value: p=<0.05

A weighing scale-based system measuring pulse transit time tracks diastolic blood pressure changes significantly better than conventional pulse arrival time, offering a potential future method for cuff-less blood pressure monitoring.

Limitations

Only young, healthy subjects were studied
ECG waveform was used to detect the fiducial points of the BCG and foot PPG waveforms, requiring further development for a fully ECG-free system
Requires a calibration procedure to convert scale PTT to BP
Scale PTT tracked systolic BP changes better than conventional PAT but not to an acceptable level

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

May support scale-based PTT for cuffless diastolic BP tracking; hypothesis-generating and requires prospective validation.

Cite This Study

Martin et al. (2016) conducted an observational in Healthy (n=22). Weighing scale-based pulse transit time (Scale PTT) vs. Conventional pulse arrival time (PAT) was evaluated on Tracking of diastolic blood pressure changes (correlation coefficient) (Correlation coefficient -0.80, p=<0.05). Weighing scale-based pulse transit time tracked diastolic blood pressure changes significantly better than conventional pulse arrival time (correlation coefficient -0.80 vs -0.60).

synapsesocial.com/papers/6a62aab150935c8f480985f3 https://doi.org/10.1038/srep39273

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Weighing Scale-Based Pulse Transit Time is a Superior Marker of Blood Pressure than Conventional Pulse Arrival Time

Study Design

Structured PICO

Main Result

Limitations

Discussion

Implication

Cite This Study

Weighing Scale-Based Pulse Transit Time is a Superior Marker of Blood Pressure than Conventional Pulse Arrival Time

Study Design

Structured PICO

Main Result

Limitations

Discussion

Implication

Cite This Study

Also Consider

Also Consider