Key result
Women face an average ~0.8-year longer delay to AF ablation than men with ischemic heart disease.
Why the study?
Atrial fibrillation is more frequent in women with ischemic heart disease, yet women with atrial fibrillation remain suboptimally treated.
Does female sex influence the time to catheter ablation and clinical outcomes in patients with atrial fibrillation and ischemic heart disease?
Cohort (n=55)
No
Does female sex influence the time to catheter ablation and clinical outcomes in patients with atrial fibrillation and ischemic heart disease?
Women with atrial fibrillation and ischemic heart disease undergo catheter ablation significantly later than men, highlighting a potential sex disparity in access to interventional care.
Potential sex disparity in ablation access for women with AF and IHD warrants awareness; leaves open outcome impact and need for prospective study.
Background: Atrial fibrillation is more common in men, but in the presence of ischemic heart disease, this arrhythmia is more frequent in women. However, like in coronary heart disease, women with atrial fibrillation are suboptimally treated. Methods: To identify particularities of ablation, in women with atrial fibrillation and ischemic heart disease. Results: 29 women and 26 men, with documented ischemic heart disease and atrial fibrillation, who underwent catheter ablation, were admitted in the study. No significant differences were registered regarding the heart rate control treatment. Electrical cardioversion was significantly higher in men, while pharmacological cardioversion was predominantly recommended in women. The ablation was performed later in women, after 2.55 ± 1.84 years versus 1.80 ± 1.05 in men (p = 0.05). The time elapsed until the ablation was performed was statistically correlated with atypical symptomatology and with the number of antiarrhythmics used prior to the ablation. There were no significant differences for the relapse of atrial fibrillation at 3 months. Quality of life at 3 months after ablation was increased in both groups. Conclusion: Catheter ablation is performed much later in women, and the causes responsible for this delay would be more atypical symptoms and a greater number of antiarrhythmics tried before the ablation.
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Irimie et al. (2022) conducted a cohort in Atrial fibrillation and ischemic heart disease (n=55). Female sex vs. Male sex was evaluated on Time elapsed until catheter ablation was performed (p=0.05). Catheter ablation was performed significantly later in women with atrial fibrillation and ischemic heart disease compared to men (2.55 ± 1.84 years vs 1.80 ± 1.05 years, p=0.05).
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