Why the study?
Sex-related differences in clinical rhythm and safety outcomes after catheter ablation for AF remained unclear.
Does female sex reduce freedom from AF/AT recurrence and increase complications in patients undergoing catheter ablation for atrial fibrillation compared to male sex?
Population
151 370 patients (34% women) across 19 observational studies undergoing catheter ablation for AF
Comparison
Women vs men
Design
Systematic review and meta-analysis of observational studies
Follow-up
2.4-year
Authors
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Women may warrant sex-specific counseling and closer post-ablation surveillance; reinforces outcome disparities in a large pooled analysis.
Does female sex reduce freedom from AF/AT recurrence and increase complications in patients undergoing catheter ablation for atrial fibrillation compared to male sex?
Women undergoing catheter ablation for atrial fibrillation experience lower efficacy, higher risk of stroke/TIA, and more major complications compared to men.
Cheng et al. (2019) studied this question.
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