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June 27, 2023Journal of Cardiovascular Electrophysiology

Catheter ablation for AFib shows similar 1-year arrhythmia recurrence and complications in women and men.

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Why the study?

Most studies evaluating AF ablation outcomes included relatively small female cohorts, leaving the impact of sex on procedure safety and outcomes unclear.

Does female sex compared to male sex affect arrhythmia recurrence and procedural complications in patients undergoing catheter ablation for atrial fibrillation?

Population

Patients undergoing AF ablation from January 1, 2014, to March 31, 2021

Comparison

Female vs male patients

Design

Retrospective study

Follow-up

1-year

Key result

Catheter ablation for atrial fibrillation showed similar 1-year arrhythmia recurrence rates between women and men (30% vs 27.7%; p=0.38) and similar procedural complication rates.

Authors

RYRitu YadavMidwestern UniversityJMJenna MilsteinJohns Hopkins UniversityJBJacob BlumJohns Hopkins University

Discussion

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Member takes

Overview

Supports equitable AF ablation consideration by sex; leaves open randomized confirmation given observational design.

Study Design

Type

Cohort

Structured PICO

Does female sex compared to male sex affect arrhythmia recurrence and procedural complications in patients undergoing catheter ablation for atrial fibrillation?

P
Population
Patients undergoing catheter ablation for atrial fibrillation from January 1, 2014, to March 31, 2021.
I
Intervention
Catheter ablation for atrial fibrillation in female patients
C
Comparator
Catheter ablation for atrial fibrillation in male patients
O
Outcome
Arrhythmia recurrence at 1-year post ablation and procedural complication rate

Main Result

Absolute Event Rate: 30% vs 27.7%

p-value: p=.38

Despite women having higher CHA2DS2-VASc scores and trying more antiarrhythmic drugs prior to ablation, there were no significant sex-based differences in 1-year arrhythmia recurrence or procedural complications following catheter ablation for atrial fibrillation.

Cite This Study

Yadav et al. (2023) conducted a cohort in Atrial fibrillation. Female sex (Catheter ablation) vs. Male sex was evaluated on Arrhythmia recurrence at 1-year post ablation (p=.38). Catheter ablation for atrial fibrillation showed similar 1-year arrhythmia recurrence rates between women and men (30% vs 27.7%; p=0.38) and similar procedural complication rates.

synapsesocial.com/papers/6a11d6ea8095bbd48eb4caa8https://doi.org/10.1111/jce.15975
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