Key result
Transcatheter pulmonary valve replacement is an alternative to surgery for pulmonary valve dysfunction, though many patients with complex morphology cannot undergo the procedure.
Why the study?
In patients with congenital heart defects and right ventricular outflow tract dysfunction, open surgery carries high risk from repeated valve replacements, making transcatheter pulmonary valve replacement an alternative.
Is transcatheter pulmonary valve replacement an effective alternative to open surgery in patients with congenital heart defects and pulmonary artery dysfunction?
Is transcatheter pulmonary valve replacement an effective alternative to open surgery in patients with congenital heart defects and pulmonary artery dysfunction?
Transcatheter pulmonary valve replacement is a viable alternative to high-risk repeated open surgeries for many patients with congenital heart defects, though anatomical limitations remain.
TPVI may support surgical alternatives in eligible patients; leaves open device development for complex RVOT and PA morphologies.
Dysfunction of the right ventricular outflow tract and pulmonary artery is often found in patients with congenital heart defects. In most cases, open surgery is often associated with high risk due to repeated pulmonary valve replacement throughout the life. Transcatheter pulmonary valve replacement is one of the most progressive achievements in the treatment of pulmonary artery dysfunction. This approach has become a clear alternative to surgical intervention in these patients. In this review, we analyzed pathophysiology of pulmonary valve dysfunction on example of tetralogy of Fallot, indications for transcatheter pulmonary valve implantation, results and possible complications. Aspects of clinical application and valve technology are also highlighted. To date, transcatheter pulmonary valve implantation is actively used as an alternative to surgical intervention for dysfunction of pulmonary valve and right ventricular outflow tract. Nevertheless, the number of patients with complex morphology of right ventricular outflow and pulmonary artery who cannot undergo percutaneous valve implantation is significant.
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Troshkinev et al. (2023) conducted a review in Congenital heart defects with right ventricular outflow tract and pulmonary artery dysfunction. Transcatheter pulmonary valve replacement vs. Surgical intervention was evaluated. Transcatheter pulmonary valve replacement is an alternative to surgery for pulmonary valve dysfunction, though many patients with complex morphology cannot undergo the procedure.
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