Key result
Carotid sinus nerve denervation reduced both the development and maintenance of hypertension in spontaneously hypertensive rats (P<0.05).
Why the study?
Does carotid sinus nerve denervation reduce arterial blood pressure in spontaneously hypertensive rats?
Does carotid sinus nerve denervation reduce arterial blood pressure in spontaneously hypertensive rats?
p-value: p=<0.05
Carotid sinus nerve denervation reduces the development and maintenance of hypertension in spontaneously hypertensive rats, highlighting the role of carotid body input in hypertension.
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CSD attenuates hypertension in SHR via lower sympathetic tone; hypothesis-generating for carotid body denervation in human hypertension.
Abdala et al. (2012) studied Hypertension. Carotid sinus nerve denervation vs. Sham-operated SHRs and Wistar rats was evaluated on Development and maintenance of hypertension (p=<0.05). Carotid sinus nerve denervation reduced both the development and maintenance of hypertension in spontaneously hypertensive rats (P<0.05).
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