Key result
Dynamic hs-TNI elevation in acute ischemic stroke patients was associated with acute coronary syndrome in 53.7% of cases, compared to 0% in patients with constant hs-TNI elevation.
Why the study?
Does serial measurement of high-sensitive troponin I to detect dynamic changes accurately identify concomitant acute coronary syndrome in acute ischemic stroke patients?
Cohort (n=834)
No
Does serial measurement of high-sensitive troponin I to detect dynamic changes accurately identify concomitant acute coronary syndrome in acute ischemic stroke patients?
Absolute Event Rate: 53.7% vs 0%
In acute ischemic stroke patients with elevated high-sensitive troponin I, serial measurements are essential because therapeutically relevant acute coronary syndrome is diagnosed only in those with dynamic troponin changes.
No takes yet. Share an insight, caveat, or question.
Elevated hs-troponin is common in stroke without ACS symptoms; leaves open whether routine testing improves outcomes or warrants cardiac workup.
Anders et al. (2013) conducted a cohort in Acute ischemic stroke (n=834). Dynamic hs-TNI elevation vs. Constant hs-TNI elevation was evaluated on Diagnosis of acute coronary syndrome (STEMI or NSTEMI). Dynamic hs-TNI elevation in acute ischemic stroke patients was associated with acute coronary syndrome in 53.7% of cases, compared to 0% in patients with constant hs-TNI elevation.
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