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July 4, 2026Bulletin of the Chemical Society of JapanOpen Access

Preparation of high internal phase emulsions utilizing hyaluronic acid and elucidation of its structure-stabilizing effect

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Authors

YSYuta ShishidoTSTakuya SagawaMHMineo Hashizume

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Overview

Randomized trial demonstrates improved emulsion stability in cosmetics, highlighting hyaluronic acid's potential as a natural stabilizer.

Key Points

  • This research aims to explore the role of hyaluronic acid in stabilizing oil-in-water high internal phase emulsions and reduce surfactant use.
  • Prepared oil-in-water high internal phase emulsions using varying concentrations of hyaluronic acid.
  • Conducted rheological measurements to analyze viscosity relationships and emulsion stability.
  • Assessed the impact of molecular weight and structure of hyaluronic acid on emulsion properties.
  • Highly concentrated emulsions were formed with less surfactant when using hyaluronic acid (HYA).
  • Rheological analysis showed a clear relationship between emulsion viscosity and aqueous phase viscosity.
  • The changes in molecular weight and structure of HYA correlated with emulsion stability improvements.

Cite This Study

Shishido et al. (2026) studied this question.

synapsesocial.com/papers/6a48a65789561a0c2d78e7ffhttps://doi.org/10.1093/bulcsj/uoag083
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