Key result
Translating genetic associations into mechanistic understanding remains essential to advance personalized AF therapies.
Design
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Mechanistic validation of AF genetic findings is required before personalized therapies can be adopted; leaves open specific clinical translation pathways.
Matthew J Read, Camila Roman, Xander H T Wehrens; Personalizing Atrial Fibrillation Therapy: Moving from Genetic Association to Mechanistic Translation, Ca
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Read et al. (2026) studied this question. Translating genetic associations into mechanistic understanding is necessary to advance personalized therapies for atrial fibrillation.
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