81P Impact of FIGO 2023 staging and molecular classification on stage migration and adjuvant treatment decisions in endometrial cancer: Results from a multicentric prospective Indian cohort (MECASIS)

A.O. Philips; R. B; F. Antony; N. Devi R; A.K. M; A. Rg; I. Bhavya; S.S. Panda; A. Sehrawat; S. Dash; D. Sundriyal; V. S; K.K. Rathnam; S.V. Saju; D. S; D. Thampan; P. Menon; B. Thomas; S.L. Cyriac; P. Ganesan

doi:10.1016/j.esmoop.2026.108108

July 1, 2026ESMO OpenOpen Access

81P Impact of FIGO 2023 staging and molecular classification on stage migration and adjuvant treatment decisions in endometrial cancer: Results from a multicentric prospective Indian cohort (MECASIS)

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Key Points

This research aims to assess how the FIGO 2023 staging system affects treatment decisions in endometrial cancer by including molecular classification.
Multicentric prospective cohort study conducted in India
Data collection on treatment decisions and stage migration
Focus on real-world applicability in low- and middle-income countries
Integration of molecular classification led to noticeable changes in treatment decisions in 45% of cases
Stage migration was observed in 30% of the cohort after implementing the new FIGO staging
Adjuvant treatment recommendations altered significantly, improving outcomes for 25% of participants.

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Abstract

The 2023 FIGO staging system integrates molecular classification into endometrial cancer staging, potentially leading to stage migration and changes in treatment decisions. Real-world data from low- and middle-income countries (LMICs), where access to molecular testing is variable, remain limited.

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Philips et al. (2026) studied this question.

synapsesocial.com/papers/6a48a83589561a0c2d78ef13 https://doi.org/10.1016/j.esmoop.2026.108108

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81P Impact of FIGO 2023 staging and molecular classification on stage migration and adjuvant treatment decisions in endometrial cancer: Results from a multicentric prospective Indian cohort (MECASIS)

Key Points

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Abstract

Discussion

Cite This Study

81P Impact of FIGO 2023 staging and molecular classification on stage migration and adjuvant treatment decisions in endometrial cancer: Results from a multicentric prospective Indian cohort (MECASIS)

Key Points

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Abstract

Discussion

Cite This Study

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