Key result
Transfemoral TAVR safely treats severe AS complicated by chronic TAAD and improves 12-month NYHA class.
Why the study?
Chronic type A aortic dissection with severe aortic stenosis represents a major therapeutic challenge, especially in patients at high surgical risk.
Does transfemoral TAVR improve symptoms and avoid complications in a high-surgical-risk patient with severe bicuspid aortic stenosis and chronic type A aortic dissection?
Case Report (n=1)
Does transfemoral TAVR improve symptoms and avoid complications in a high-surgical-risk patient with severe bicuspid aortic stenosis and chronic type A aortic dissection?
Transfemoral TAVR is feasible and can provide symptomatic benefit in carefully selected high-surgical-risk patients with severe aortic stenosis and chronic type A aortic dissection when true lumen access is secured.
May support TAVR as an option in select chronic TAAD with severe AS; leaves open need for prospective data before broader adoption.
BACKGROUND: Chronic type A aortic dissection (TAAD) with severe aortic stenosis (AS) represents a major therapeutic challenge, particularly in patients at high surgical risk. CASE SUMMARY: An 83-year-old woman presented with acute decompensated heart failure (NYHA functional class IV). Imaging revealed severe bicuspid AS and chronic TAAD extending to the infrarenal abdominal aorta. Given the high surgical risk, transfemoral transcatheter aortic valve replacement (TAVR) was performed under transesophageal echocardiography guidance with confirmation of true lumen access, without complications. At 12 months postoperatively, the patient improved to NYHA functional class II with stable dissection. DISCUSSION: In selected patients with stable chronic TAAD and no surgical options, TAVR may provide symptomatic benefit when anatomical features are favorable and procedural strategy minimizes aortic wall stress. TAKE-HOME MESSAGE: TAVR may be feasible in carefully selected patients with chronic TAAD and severe AS when true lumen access is secured and imaging guidance is used to reduce the risk of dissection progression.
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González-Aguilar et al. (2026) conducted a case report in Chronic type A aortic dissection and severe aortic stenosis (n=1). Transfemoral transcatheter aortic valve replacement (TAVR) was evaluated. Transfemoral TAVR was successfully performed without complications in an 83-year-old woman with severe AS and chronic TAAD, improving her symptoms to NYHA class II at 12 months.
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