Early ganglion stellate blockade as part of two-step treatment algorithm suppresses electrical storm and need for intubation
Key result
Early stellate ganglion blockade significantly reduced ICD shocks by 86.8% and anti-tachycardiac pacing by 65.9% at 48 hours in patients with electrical storm (P<0.001).
Why the study?
To evaluate the short-term efficacy of a two-step algorithm combining standard anti-arrhythmic measures with early ultrasound-guided stellate ganglion blockade, and test whether it prevents the need for intubation in electrical storm.
Does early ultrasound-guided stellate ganglion blockade as part of a two-step algorithm reduce ICD shocks, anti-tachycardiac pacing, and the need for intubation in patients with electrical storm?
Population
59 ICD patients with 70 electrical storm events requiring SGB
Comparison
Two-step algorithm with standard anti-arrhythmic measures and early ultrasound-guided SGB
Design
Single-center study
Authors
Discussion
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Member takes
Implication
May support SGB in electrical storm to cut ICD therapies; hypothesis-generating, needs RCTs before practice change.
Study Design
Type
Cohort (n=59)
Multicenter
No
Structured PICO
Does early ultrasound-guided stellate ganglion blockade as part of a two-step algorithm reduce ICD shocks, anti-tachycardiac pacing, and the need for intubation in patients with electrical storm?
P
Population
59 patients (mean age 67.7 years, 20% female) with electrical storm and implantable cardioverter-defibrillators treated with early stellate ganglion blockade.
E
Exposure
Two-step algorithm comprising standard anti-arrhythmic measures and early ultrasound-guided stellate ganglion blockade (SGB)
O
Outcome
Reduction in shocks and anti-tachycardiac pacing (ATP) at 48 hours after SGB, and need for intubation
Main Result
p-value: p=<0.001
Early ultrasound-guided stellate ganglion blockade is a safe and highly effective strategy to rapidly reduce ventricular arrhythmia burden and avoid intubation in patients with electrical storm.
Cite This Study
Jiravský et al. (2023) conducted a cohort in Electrical storm (n=59). Early ultrasound-guided stellate ganglion blockade was evaluated on Percentage reduction in shocks at 48 hours after stellate ganglion blockade (p=<0.001). Early stellate ganglion blockade significantly reduced ICD shocks by 86.8% and anti-tachycardiac pacing by 65.9% at 48 hours in patients with electrical storm (P<0.001).