Key result
Inducibility at electrophysiology study independently predicted appropriate ICD therapy in patients with ARVD/C (HR 2.28; 95% CI 1.10-4.70; P=0.025).
Population
312 patients with definite arrhythmogenic right ventricular dysplasia/cardiomyopathy who received an…
Design
Cohort
Follow-up
8.8±7.33 years
Authors
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May aid ARVC risk stratification via EP study and PVC burden; leaves open prospective validation before guiding decisions.
Cohort (n=312)
Hazard Ratio: 2.28 (95% CI 1.1–4.7)
p-value: p=0.025
In patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy, inducibility at EP study, younger age, and high PVC burden are independent predictors of appropriate ICD therapy and potentially fatal ventricular arrhythmias, aiding in risk stratification.
Orgeron et al. (2017) conducted a cohort in Arrhythmogenic right ventricular dysplasia/cardiomyopathy (n=312). Inducibility at electrophysiology study vs. No inducibility at electrophysiology study was evaluated on Any appropriate ICD therapy (HR 2.28, 95% CI 1.10-4.70, p=0.025). Inducibility at electrophysiology study independently predicted appropriate ICD therapy in patients with ARVD/C (HR 2.28; 95% CI 1.10-4.70; P=0.025).
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