Key result
Analysis of complete genomes of E25SD, E30SD, CVB1SD and E6SD isolated from HFMD patients revealed they formed novel subgenogroups and underwent frequent recombination.
Population
233 clinical specimens from patients with severe hand, foot and mouth disease during 2010-2011 in Linyi…
Design
Other
Authors
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Supports virological surveillance for evolving HEV-B in HFMD; hypothesis-generating on recombination and subgenogroup virulence.
Observational (n=233)
HEV-B isolates from severe HFMD patients in China demonstrate frequent recombination and form novel subgenogroups, highlighting the need for persistent virological surveillance.
Zhang et al. (2013) conducted an observational in Hand, foot and mouth disease (HFMD) (n=233). Human enterovirus B (HEV-B) was evaluated on Epidemiology and molecular characteristics of HEV isolates. Analysis of complete genomes of E25SD, E30SD, CVB1SD and E6SD isolated from HFMD patients revealed they formed novel subgenogroups and underwent frequent recombination.
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