Key result
Transcatheter pulmonary valve replacement showed no significant difference in risk-adjusted early major morbidity and mortality compared to surgical replacement (unadjusted 3.8% vs 11.7%, p=0.04).
Why the study?
Does TPVR compared to SPVR reduce early major morbidity and mortality in patients undergoing pulmonary valve replacement?
Population
223 patients undergoing pulmonary valve replacement at a single institution between January 2006 and January…
Comparison
Transcatheter pulmonary valve replacement (TPVR) vs Surgical pulmonary valve replacement (SPVR)
Design
Cohort
Follow-up
early (in-hospital)
Authors
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Comparable risk-adjusted early outcomes support equipoise between TPVR and SPVR; leaves open need for randomized confirmation.
Cohort (n=223)
No
Does TPVR compared to SPVR reduce early major morbidity and mortality in patients undergoing pulmonary valve replacement?
Absolute Event Rate: 3.8% vs 11.7%
p-value: p=0.04
TPVR and SPVR have similar risk-adjusted early major morbidity and mortality, though TPVR is associated with a significantly shorter hospital length of stay with similar total costs.
Steinberg et al. (2017) conducted a cohort in Pulmonary valve disease requiring replacement (n=223). Transcatheter pulmonary valve replacement (TPVR) vs. Surgical pulmonary valve replacement (SPVR) was evaluated on Early major morbidity and mortality (p=0.04). Transcatheter pulmonary valve replacement showed no significant difference in risk-adjusted early major morbidity and mortality compared to surgical replacement (unadjusted 3.8% vs 11.7%, p=0.04).
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