Key result
Continuous spinal anesthesia resulted in fewer hypotension episodes compared to propofol TCI and sevoflurane (0 vs 11.5 and 10 episodes; P<0.001) in elderly patients with cardiac comorbidities.
Why the study?
Does continuous spinal anesthesia reduce hypotension compared to propofol or sevoflurane general anesthesia in elderly patients with cardiac comorbidities undergoing hip fracture surgery?
Population
n=45 patients older than 75 years, with American Society of Anesthesiologists physical status III or IV…
Comparison
Continuous spinal anesthesia with titrated 2.5… vs Propofol target-controlled infusion or…
Design
RCT, randomized
Authors
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May support continuous spinal anesthesia to limit hypotension in high-risk elderly; leaves open confirmation via randomized trials.
RCT (n=45)
randomized
Does continuous spinal anesthesia reduce hypotension compared to propofol or sevoflurane general anesthesia in elderly patients with cardiac comorbidities undergoing hip fracture surgery?
Absolute Event Rate: 0% vs 11.5%
p-value: p=<0.001
In elderly patients with cardiac comorbidities undergoing hip fracture surgery, continuous spinal anesthesia provides better hemodynamic stability with fewer hypotension episodes than target-controlled general anesthesia.
Biboulet et al. (2012) conducted an RCT in Hip fracture with cardiac comorbidities (n=45). Continuous spinal anesthesia (CSA) vs. Propofol target-controlled infusion (TCI) or sevoflurane (SEVO) was evaluated on Number of hypotension episodes (p=<0.001). Continuous spinal anesthesia resulted in fewer hypotension episodes compared to propofol TCI and sevoflurane (0 vs 11.5 and 10 episodes; P<0.001) in elderly patients with cardiac comorbidities.
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