Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 1, 2003European Journal of Anaesthesiology

Randomized comparison between sevoflurane anaesthesia and unilateral spinal anaesthesia in elderly patients undergoing orthopaedic surgery

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does sevoflurane anaesthesia improve postoperative cognitive function or hemodynamic stability compared to unilateral spinal anaesthesia in elderly patients undergoing hip fracture repair?

Population

30 elderly patients (>65 yr) undergoing hip fracture repair

Comparison

Volatile induction and maintenance anaesthesia… vs Unilateral spinal anaesthesia with hyperbaric…

Design

RCT, randomly allocated

Follow-up

7 days after surgery

Authors

ACA. CasatiUniversity of ParmaGAGiorgio AldegheriUniversity of ParmaFVF. VinciguerraOspedale San Giuseppe

Discussion

Loading...

Member takes

Implication

Spinal anesthesia reduces hypotension and speeds PACU discharge versus sevoflurane with equivalent cognition; extends RCT evidence favoring regional techniques in elderly hip fracture repair.

Structured PICO

Does sevoflurane anaesthesia improve postoperative cognitive function or hemodynamic stability compared to unilateral spinal anaesthesia in elderly patients undergoing hip fracture repair?

P
Population
30 elderly patients (>65 yr) undergoing hip fracture repair
I
Intervention
Volatile induction and maintenance anaesthesia with sevoflurane (induced at 5% inspired concentration, adjusted to maintain cardiovascular stability)
C
Comparator
Unilateral spinal anaesthesia with hyperbaric bupivacaine 7.5 mg 0.5%
O
Outcome
Hypotension (decrease in systolic arterial pressure > 20% from baseline), hypertension or bradycardia (heart rate < 50 beats min−1) requiring treatment, length of stay in the postanaesthesia care unit, and cognitive functions (Mini Mental State Examination test)safety

Sevoflurane anaesthesia provides rapid emergence without increased postoperative cognitive depression compared to unilateral spinal anaesthesia, though it is associated with more frequent hypotension and longer PACU stay.

Cite This Study

Casati et al. (2003) studied this question.

synapsesocial.com/papers/6a706ae72163a0a01bc4a2c7https://doi.org/10.1097/00003643-200308000-00009
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Induction of Anesthesia in the Elderly Ambulatory Patient: A Double-Blinded Comparison of Propofol and Sevoflurane2001 · 58 citations
  2. 2Comparison of Arterial Baroreflex Function in Humans Anesthetized with Enflurane or Isoflurane1989 · 40 citations
  3. 3FUNCTIONAL CHANGES IN AUTONOMIC NERVOUS RESPONSES WITH AGEING1980 · 160 citations