September 1, 2012EuroIntervention
Impact of CT-guided valve sizing on post-procedural aortic regurgitation in transcatheter aortic valve implantation
Key result
CT-guided valve sizing in TAVI significantly reduced the incidence of post-procedural aortic regurgitation ≥ grade 2 compared to TEE sizing (15.4% vs. 24.0%, p=0.044).
Why the study?
Does CT-guided valve sizing reduce post-procedural aortic regurgitation in TAVI recipients compared to TEE-guided sizing?
Population
350 consecutive TAVI recipients, mean age 83.2 ± 6.4 years, logistic EuroSCORE 22.4 ± 11.2%
Comparison
CT-guided valve sizing for transcatheter aortic… vs Transoesophageal echocardiography-guided valve…
Design
Cohort
Follow-up
post-procedural
Authors
Discussion
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Member takes
Implication
May favor CT-guided TAVI sizing to lower moderate AR risk; hypothesis-generating pending randomized trials.
Study Design
Type
Cohort (n=350)
Structured PICO
Does CT-guided valve sizing reduce post-procedural aortic regurgitation in TAVI recipients compared to TEE-guided sizing?
P
Population
350 consecutive TAVI recipients with a mean age of 83.2 years and a mean logistic EuroSCORE of 22.4%.
E
Exposure
CT-guided valve sizing for transcatheter aortic valve implantation (TAVI)
C
Comparator
Transoesophageal echocardiography (TEE)-guided valve sizing for TAVI
O
Outcome
Post-procedural aortic regurgitation (AR) ≥ grade 2surrogate
Main Result
Absolute Event Rate: 15.4% vs 24%
p-value: p=0.044
CT-guided valve sizing for TAVI significantly reduces the incidence of post-procedural aortic regurgitation compared to TEE-guided sizing, likely due to larger valve implant sizes.
Cite This Study
Hayashida et al. (2012) conducted a cohort in Transcatheter aortic valve implantation (TAVI) (n=350). CT-guided valve sizing vs. TEE-guided valve sizing was evaluated on Post-procedural aortic regurgitation ≥ grade 2 (p=0.044). CT-guided valve sizing in TAVI significantly reduced the incidence of post-procedural aortic regurgitation ≥ grade 2 compared to TEE sizing (15.4% vs. 24.0%, p=0.044).