Key result
Abdominal obesity, present in 49.3% of patients with symptomatic carotid disease, was significantly associated with metabolic syndrome, hyperglycemia, and high serum uric acid.
Why the study?
Is abdominal obesity associated with other cardiovascular risk factors in patients with symptomatic carotid disease?
Cross-Sectional (n=657)
Is abdominal obesity associated with other cardiovascular risk factors in patients with symptomatic carotid disease?
In patients with symptomatic carotid disease, abdominal obesity is significantly associated with metabolic syndrome and its components, highlighting a clustered cardiovascular risk profile.
Abdominal obesity may flag higher metabolic risk in symptomatic carotid disease; leaves open causal effects and intervention benefits.
INTRODUCTION: Obesity, particularly visceral obesity, is considered one of major risk factors for cardiovascular events. OBJECTIVES: The aim of the present study was to investigate relationship between abdominal obesity and other cardiovascular risk factors. METHODS: The cross-sectional study involved 657 consecutive patients with verified carotid atherosclerosis. Carotid atherosclerosis was estimated by high resolution B-mode ultrasonography. Abdominal obesity was defined as waist circumference > 102 cm in men and > 88 cm in women. RESULTS: Abdominal obesity was present in 324 (49.3%) participants. Multivariate analyses showed that abdominal obesity was significantly positively associated with female sex, increased Baecke's Work Index of physical activity at work, years of school completed < 12, metabolic syndrome, increased triglycerides, hyperglycemia and high serum uric acid. Smoking, alcohol consumption, physical inactivity, hypertension, increased total cholesterol, increased HDL and LDL cholesterols, increased high sensitive C-reactive protein, increased fibrinogen, anti-lipid therapy and anti-diabetic therapy were not significantly related to abdominal obesity. CONCLUSION: Abdominal obesity among patients with symptomatic carotid disease is significantly related to other cardiovascular risk factors, especially metabolic syndrome, metabolic syndrome components and high level of serum uric acid.
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Maksimović et al. (2013) conducted a cross-sectional in symptomatic carotid disease (n=657). Abdominal obesity vs. Absence of abdominal obesity was evaluated on Association with other cardiovascular risk factors. Abdominal obesity, present in 49.3% of patients with symptomatic carotid disease, was significantly associated with metabolic syndrome, hyperglycemia, and high serum uric acid.
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