Why the study?
No single modality has been adopted as an optimal treatment for Kimura disease.
This review summarizes the pathophysiology and current treatment approaches for Kimura disease, highlighting the lack of a single optimal treatment modality.
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Ongoing challenges persist in Kimura disease management; leaves open need for prospective trials to define optimal therapy.
Kimura disease (KD) is a chronic inflammatory disorder that frequently involves the subcutaneous tissue of the head and neck regions. It often manifests as regional lymphadenopathy or salivary gland enlargement in the affected area. The histologic architecture of the lymph nodes in KD patients is preserved, while the affected tissues show follicular hyperplasia and eosinophilic infiltration. No single modality has been adopted as an optimal treatment for KD. This article concentrates on the fundamental features of KD and reviews current approaches to its treatment.
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Kim et al. (2022) conducted a review in Kimura disease. Various treatments (surgery, radiotherapy, corticosteroids, immunosuppressants) was evaluated.
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