What question did this study set out to answer?

This research aims to assess the association between albumin-based inflammatory indices and neonatal outcomes in pregnancies affected by intrahepatic cholestasis of pregnancy.

July 5, 2026BMC Pregnancy and ChildbirthOpen Access

Association of albumin-based inflammatory indices with adverse neonatal outcomes in intrahepatic cholestasis of pregnancy: a retrospective comparative study

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SÇSevil Çiçekİstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi BKBilge Kapudereİstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi YPYasemin Beyza Kaya Parspancıİstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi

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Implication

Retrospective comparative study investigates albumin-based indices affecting neonatal outcomes in pregnancies affected by intrahepatic cholestasis, highlighting implications for care.

Key Points

This research aims to assess the association between albumin-based inflammatory indices and neonatal outcomes in pregnancies affected by intrahepatic cholestasis of pregnancy.
Included 277 pregnant women delivering at a tertiary referral center from January 2020 to December 2025.
Compared perinatal and neonatal outcomes between women with intrahepatic cholestasis and controls.
Performed multivariable logistic regression analysis to identify predictors of NICU admission within the ICP group.
Lower gestational age and neonatal birth weight, with a higher incidence of preterm birth and NICU admissions in the ICP group.
Higher leukocyte-to-albumin ratio, neutrophil-to-albumin ratio, and monocyte-to-albumin ratio were significantly associated with NICU admissions.
In multivariable analysis, higher LAR and preterm birth <37 weeks remained independently associated with NICU admission.

Cite This Study

Çiçek et al. (2026) studied this question.

synapsesocial.com/papers/6a49f411f5d1d45b287ffbeb https://doi.org/10.1186/s12884-026-09555-7

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Implication

Retrospective comparative study investigates albumin-based indices affecting neonatal outcomes in pregnancies affected by intrahepatic cholestasis, highlighting implications for care.

Association of albumin-based inflammatory indices with adverse neonatal outcomes in intrahepatic cholestasis of pregnancy: a retrospective comparative study

Discussion

Member takes

Implication

Key Points

Cite This Study

Association of albumin-based inflammatory indices with adverse neonatal outcomes in intrahepatic cholestasis of pregnancy: a retrospective comparative study

Discussion

Member takes

Implication

Key Points

Cite This Study

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