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December 6, 2025Journal of Perinatal MedicineOpen Access

Association between FAR, PAR, APRI and adverse neonatal outcomes in pregnancies complicated by intrahepatic cholestasis

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Authors

NKNeval Çayönü KahramanMinistry of Health BÇBetül Tokgöz ÇakırÇankaya University FAFulya AkınUniversity of Health Sciences Antigua

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Implication

Retrospective study shows elevated biomarkers linked to adverse neonatal outcomes in intrahepatic cholestasis, indicating need for further evaluation.

Key Points

Elevated levels of FAR and APRI found in intrahepatic cholestasis pregnancies, yet predictive value for adverse outcomes is limited.
Neonates with adverse outcomes had significantly higher FAR levels, indicating a potential risk factor.
Retrospective comparative study assessed biomarker performance using diagnostic performance metrics across 165 women diagnosed with IHCP.
Further large-scale studies needed to solidify the role of these biomarkers in clinical practice.

Cite This Study

Kahraman et al. (2025) studied this question.

synapsesocial.com/papers/694020f72d562116f28fb434 https://doi.org/10.1515/jpm-2025-0323

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Implication

Retrospective study shows elevated biomarkers linked to adverse neonatal outcomes in intrahepatic cholestasis, indicating need for further evaluation.

Association between FAR, PAR, APRI and adverse neonatal outcomes in pregnancies complicated by intrahepatic cholestasis

Discussion

Member takes

Implication

Key Points

Cite This Study

Association between FAR, PAR, APRI and adverse neonatal outcomes in pregnancies complicated by intrahepatic cholestasis

Discussion

Member takes

Implication

Key Points

Cite This Study

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