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August 21, 2025MedicineOpen Access

Utility of the fibrinogen–albumin ratio and CRP–albumin ratio in previable preterm early membrane rupture

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Analysis reveals fibrinogen-albumin ratio predicts abortion risk in women with previable PPROM, highlighting its clinical significance.

Fibrinogen-to-albumin ratio predicts abortion risk in previable PPROM patients, showing a strong correlation.
Patients with previable PPROM had significantly higher C-reactive protein and fibrinogen-albumin ratios than controls, indicating inflammation.
Analysis involved 79 pregnant women, examining inflammatory markers related to outcomes of pregnancies under previable PPROM.
Fibrinogen-albumin ratio showed the highest predictive value for abortion with 76.2% sensitivity and 85.7% specificity.

Uysal et al. (2025) studied this question.

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