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This research aims to evaluate the antimalarial activity and safety of aqueous extracts from Sargassum fluitans and Sargassum natans.

Antimalarial activity of Sargassum fluitans and Sargassum natans stranded along the Caribbean coast of Panama

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Randomized trial evaluates antimalarial activity of Sargassum extracts, indicating promising treatment options.

This research aims to evaluate the antimalarial activity and safety of aqueous extracts from Sargassum fluitans and Sargassum natans.
Aqueous extracts prepared from Sargassum species at 50°C.
In vitro antiplasmodial activity assessed against P. falciparum HB3 using the PicoGreen assay and microscopy.
Cytotoxicity evaluated in Vero cells via the MTT assay.
S. fluitans showed up to 97.35% inhibition of parasite growth at 10% v/v; S. natans showed 96.37%.
Low cytotoxicity observed in Vero cells with 0%-8% growth inhibition at 1.25% v/v.
Microscopic analyses confirmed significant morphological alterations in parasites.

Correoso et al. (2026) studied this question.

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