Key result
The proposed 3D joint T1/T2 sequence provided motion-compensated isotropic-resolution T1 and T2 maps with high linear correlation to phantom spin echo measurements (R2=0.98 and 0.99).
Why the study?
To develop a free-breathing isotropic-resolution whole-heart joint T1 and T2 mapping sequence with Dixon-encoding providing coregistered 3D maps and anatomical water/fat images in a single ~9 min scan.
A novel 3D whole-heart joint T1/T2 mapping sequence with Dixon-encoding provides accurate, coregistered T1 and T2 maps along with anatomical water/fat images in a single 9-minute scan.
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Feasibility shown in phantoms; leaves open in vivo validation before clinical cardiac use.
Milotta et al. (2020) studied Healthy (n=10). 3D whole-heart isotropic-resolution motion-compensated joint T1/T2 mapping and water/fat imaging sequence vs. Standard 2D MOLLI T1 mapping, 2D bSSFP T2 mapping, and 3D T2-prepared Dixon coronary MRA was evaluated on T1 and T2 quantification and visualization of cardiac anatomy and pericardial fat. The proposed 3D joint T1/T2 sequence provided motion-compensated isotropic-resolution T1 and T2 maps with high linear correlation to phantom spin echo measurements (R2=0.98 and 0.99).
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