Key result
Frailty was associated with a higher risk of all-cause 30-day readmission (OR 1.18; 95% CI 1.14-1.22) and in-hospital mortality (OR 1.52; 95% CI 1.40-1.66) among older patients with heart failure.
Why the study?
The study examined whether adding frailty to traditional risk-adjusted models could improve the predictability of unplanned 30-day readmission and mortality among patients with heart failure.
Does frailty increase the risk of 30-day unplanned readmission and in-hospital mortality in patients ≥65 years hospitalized for heart failure?
Cohort (n=819,854)
Yes
Does frailty increase the risk of 30-day unplanned readmission and in-hospital mortality in patients ≥65 years hospitalized for heart failure?
The inclusion of frailty in risk-prediction models significantly improves the ability to predict 30-day unplanned readmissions and in-hospital mortality among older adults hospitalized for heart failure.
Answers are grounded in this paper and cite their sources.
Supports frailty inclusion in HF readmission and mortality models for older adults; leaves open prospective validation and outcome impact.
Objectives: This study examined how frailty in traditional risk-adjusted models could improve the predictability of unplanned 30-day readmission and mortality among heart failure patients. Methods: This study was a retrospective analysis of Nationwide Readmissions Database data collected during the years 2010–2018. All patients ≥65 years who had a principal diagnosis of heart failure were included in the analysis. The Johns Hopkins Adjusted Clinical Groups frailty-defining diagnosis indicator was used to identify frail patients. Results: There was a total of 819,854 patients admitted for heart failure during the study period. Among them, 63,302 (7.7%) were frail. In the regression analysis, the risk of all-cause 30-day readmission (OR, 1.18; 95% CI, 1.14–1.22) and in-hospital mortality (OR, 1.52; 95% CI, 1.40–1.66) were higher in patients with frailty. Discussion: Inclusion of frailty in comorbidity-based risk-prediction models significantly improved the predictability of unplanned 30-day readmission and in-hospital mortality.
No takes yet. Share an insight, caveat, or question.
Rubens et al. (2023) conducted a cohort in Heart failure (n=819,854). Frailty vs. Non-frail patients was evaluated on All-cause 30-day readmission (OR 1.18, 95% CI 1.14-1.22). Frailty was associated with a higher risk of all-cause 30-day readmission (OR 1.18; 95% CI 1.14-1.22) and in-hospital mortality (OR 1.52; 95% CI 1.40-1.66) among older patients with heart failure.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: