Key result
Right ventricular dysfunction, measured by lower tricuspid annular plane systolic excursion (TAPSE), was independently associated with an increased risk of cardiovascular events following MitraClip therapy (HR 0.788).
Why the study?
Little is known regarding the impact of right ventricular function on clinical outcomes following MitraClip therapy.
Does right ventricular dysfunction impact clinical outcomes following transcatheter mitral valve repair?
Cohort (n=77)
No
Does right ventricular dysfunction impact clinical outcomes following transcatheter mitral valve repair?
Answers are grounded in this paper and cite their sources.
Objective: Little is known regarding the impact of right ventricular (RV) function on clinical outcomes following MitraClip therapy. The aim of this study was to investigate the prognostic impact of RV dysfunction and its cut-off value following MitraClip therapy.
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Kuwata et al. (2022) conducted a cohort in Mitral regurgitation (n=77). Right ventricular dysfunction (assessed by TAPSE) vs. Preserved right ventricular function was evaluated on Cardiovascular events (cardiovascular death and rehospitalization for heart failure) (HR 0.788, 95% CI 0.788-0.987, p=0.029). Right ventricular dysfunction, measured by lower tricuspid annular plane systolic excursion (TAPSE), was independently associated with an increased risk of cardiovascular events following MitraClip therapy (HR 0.788).
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