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January 14, 2005Coronary Artery Disease431 citations

The right ventricle in pulmonary hypertension

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KCKelly ChinNKNick H.S. KimLRLewis J. Rubin

Key Result

This review summarizes the normal structure and function of the right ventricle and the impact of pulmonary arterial hypertension and its treatments on right ventricular function.

Key Points

  • The aim is to understand the role of right ventricular function in pulmonary arterial hypertension and its implications for patient outcomes.
  • Review the normal structure and function of the right ventricle.
  • Summarize the effects of pulmonary arterial hypertension and its treatments on right ventricular function.
  • Right ventricular function is a key determinant of symptoms in pulmonary arterial hypertension.
  • The degree of vascular injury does not solely predict survival; right ventricular integrity is crucial.

Structured PICO

P
Population
Patients with pulmonary arterial hypertension (PAH)

Right ventricular function, rather than the degree of vascular injury, is the major determinant of symptoms and survival in pulmonary arterial hypertension.

Abstract

Pulmonary arterial hypertension (PAH) is a term used to classify a variety of conditions that share in common an injury to the pulmonary vasculature that produces elevations in pulmonary arterial pressure. However, it is the integrity of right ventricular function, rather than the degree of vascular injury, that is the major determinant of symptoms and survival in PAH. The article will review the normal structure and function of the right ventricle and summarize the impact of PAH and its treatments on right ventricular function.

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Cite This Study

Chin et al. (2005) conducted a review in Pulmonary arterial hypertension. This review summarizes the normal structure and function of the right ventricle and the impact of pulmonary arterial hypertension and its treatments on right ventricular function.

synapsesocial.com/papers/6a4c4212028ea97264ab7624https://doi.org/10.1097/00019501-200502000-00003
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pressure and Volume Loading of the Right Ventricle Have Opposite Effects on Left Ventricular Ejection Fraction1995 · 179 citations
  2. 2Comparison of Doppler echocardiography and right heart catheterization to assess pulmonary hypertension in systemic sclerosis1997 · 326 citations
  3. 3Ventricular mass index using magnetic resonance imaging accurately estimates pulmonary artery pressure2002 · 187 citations
  4. 4Role of Endogenous Endothelin in Chronic Heart Failure1997 · 361 citations
  5. 5Lack of association between angiotensin converting enzyme (ACE) genotype, serum ACE activity, and haemodynamics in patients with primary pulmonary hypertension: Table 12003 · 21 citations