Key result
An enlarged left atrial volume index was independently associated with a higher prevalence of positive left atrial D-dimer in patients with paroxysmal atrial fibrillation (OR 2.245).
Why the study?
Does left atrial volume index predict left atrial coagulation activity in patients with paroxysmal atrial fibrillation?
Population
127 patients with paroxysmal atrial fibrillation undergoing AF ablation, including 100 patients with…
Comparison
Assessment of left atrial volume index and… vs Systemic circulation D-dimer levels; continuous…
Design
Cross-sectional
Authors
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LA enlargement may flag local hypercoagulability in paroxysmal AF; hypothesis-generating and should not yet change practice.
Observational (n=127)
No
Does left atrial volume index predict left atrial coagulation activity in patients with paroxysmal atrial fibrillation?
Odds Ratio: 2.245 (95% CI 1.194–4.626)
p-value: p=0.011
In patients with paroxysmal atrial fibrillation, an enlarged left atrial volume index predicts higher local coagulation activity, which can be mitigated by continuous warfarin therapy during ablation.
Yashiro et al. (2014) conducted an observational in Paroxysmal Atrial Fibrillation (n=127). Left atrial volume index (per 15 ml/m2 increase) was evaluated on Positive left atrial D-dimer (≥ 0.5 µg/ml) (OR 2.245, 95% CI 1.194-4.626, p=0.011). An enlarged left atrial volume index was independently associated with a higher prevalence of positive left atrial D-dimer in patients with paroxysmal atrial fibrillation (OR 2.245).
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