January 23, 2014Journal of Interventional Cardiology
Impact of Myocardial Reperfusion Status on QT Dispersion After Successful Recanalization of the Infarct‐Related Artery in Acute Myocardial Infarction
Key result
Adequate myocardial reperfusion (MBG 3) after primary PCI for anterior STEMI was associated with a significant decrease in QT dispersion (39 ± 16 ms) compared to MBG 0-2 (P<0.001).
Why the study?
Does adequate myocardial tissue perfusion (MBG 3) after successful recanalization improve QT dispersion in patients with first anterior STEMI?
Population
40 patients who underwent primary percutaneous coronary intervention for their first anterior acute…
Comparison
Primary percutaneous coronary intervention… vs Primary percutaneous coronary intervention…
Design
Cohort
Follow-up
Immediate post-procedure
Authors
Discussion
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Implication
MBG 3 reperfusion may signal lower arrhythmic risk after anterior STEMI PCI; extends perfusion benefit to QT dispersion as electrical marker.
Study Design
Type
Observational (n=40)
Structured PICO
Does adequate myocardial tissue perfusion (MBG 3) after successful recanalization improve QT dispersion in patients with first anterior STEMI?
P
Population
40 patients undergoing primary percutaneous coronary intervention for their first anterior acute ST-elevation myocardial infarction.
E
Exposure
Primary percutaneous coronary intervention achieving adequate myocardial tissue perfusion (final myocardial blush grade [MBG] 3).
C
Comparator
Primary percutaneous coronary intervention achieving inadequate myocardial tissue perfusion (final MBG 0-1 or 2).
O
Outcome
QT dispersion (QTd) after recanalization.surrogate
Main Result
Effect estimate: standardized regression coefficient -0.628
p-value: p=<0.001
Achieving adequate myocardial tissue perfusion (MBG 3) during primary PCI for anterior STEMI is associated with prompt improvement in QT dispersion, suggesting better electrical stability.
Cite This Study
Fukushima et al. (2014) conducted an observational in Anterior acute ST-elevation myocardial infarction (n=40). Myocardial blush grade (MBG) 3 vs. MBG 0-2 was evaluated on QT dispersion (QTd) after recanalization (standardized regression coefficient -0.628, p=<0.001). Adequate myocardial reperfusion (MBG 3) after primary PCI for anterior STEMI was associated with a significant decrease in QT dispersion (39 ± 16 ms) compared to MBG 0-2 (P<0.001).