What question did this study set out to answer?

The study aimed to analyze how the introduction of the PCV13 vaccine and the COVID-19 pandemic impacted antibiotic resistance in invasive pneumococcal disease (IPD).

July 7, 2026PneumoniaOpen Access

Antibiotic non-susceptibility associated serotypes of invasive pneumococcal disease - a nationwide population study from Switzerland, 2012–2022

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The study aimed to analyze how the introduction of the PCV13 vaccine and the COVID-19 pandemic impacted antibiotic resistance in invasive pneumococcal disease (IPD).
Included 8747 invasive pneumococcal disease cases from Swiss surveillance (2012-2022).
Performed regression analyses to identify trends and associations with antibiotic resistance.
Correlated vaccine and non-vaccine serotypes with resistance patterns.
Erythromycin and cotrimoxazole non-susceptibility decreased significantly (IRR: 0.9, p < 0.001).
Penicillin non-susceptibility remained constant with a dip from 9.2% (2012) to 4.7% (2022).
Specific PCV13 serotypes were linked to non-susceptibility, while non-PCV13 serotypes showed connections to multi-drug resistance.

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Implication

Nationwide study examines the link between vaccination, serotypes, and antibiotic resistance trends.

Cite This Study

Just et al. (2026) studied this question.

synapsesocial.com/papers/6a4c9687331bc25c9e5f3f49 https://doi.org/10.1186/s41479-026-00203-4

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Antibiotic non-susceptibility associated serotypes of invasive pneumococcal disease - a nationwide population study from Switzerland, 2012–2022

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Discussion

Implication

Cite This Study

Antibiotic non-susceptibility associated serotypes of invasive pneumococcal disease - a nationwide population study from Switzerland, 2012–2022

Key Points

Discussion

Implication

Cite This Study

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