Key result
A BNP level of <250 pg/mL measured early after the onset of acute pulmonary edema supports the diagnosis of acute lung injury with 90% specificity and an AUC of 0.71.
Why the study?
Does a BNP level ≤250 pg/mL accurately diagnose acute lung injury and exclude cardiogenic pulmonary edema in critically ill patients?
Cohort (n=204)
Single-blind (reference standard assessors blinded to BNP)
No
Does a BNP level ≤250 pg/mL accurately diagnose acute lung injury and exclude cardiogenic pulmonary edema in critically ill patients?
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Rana et al. (2006) conducted a cohort in Acute pulmonary edema (n=204). B-type natriuretic peptide (BNP) testing vs. Reference standard (clinical data integrated by experts) was evaluated on Diagnosis of acute lung injury (AUC 0.71). A BNP level of <250 pg/mL measured early after the onset of acute pulmonary edema supports the diagnosis of acute lung injury with 90% specificity and an AUC of 0.71.
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