Key result
Young subjects exhibited higher approximate and sample entropy and lower Hurst exponents in their RR interval time series compared to adult subjects, indicating greater complexity.
Why the study?
There is no consensus on the choice of input parameter values for approximate entropy and sample entropy when evaluating fractal time series complexity.
Entropy-based methods and the Hurst exponent can differentiate the complexity and self-similarity of RR interval time series between young and adult subjects.
Answers are grounded in this paper and cite their sources.
ApEn/SampEn analysis of fractal series is hypothesis-generating; leaves open routine cardiovascular signal applications pending validation.
The paper discusses the analysis of simulated and real fractal time series by applying approximate entropy (ApEn) and sample entropy (SampEn) to determine the complexity and predictability of the time series. The simulated fractal time series are based on the Fractal Gaussian Noise with different values of the Hurst exponent and different lengths. To study the accuracy of the simulated time series, the method of detrended fluctuation analysis was applied, which determines the value of the Hurst exponent. The results obtained on the basis of relative standard error (RSE) show that the simulated time series have a high degree of accuracy, as the RSE is less than 2% for all input values of the Hurst exponent. Studies show that ApEn and SampEn are methods that are very sensitive to input parameters: subseries length, tolerance value and data length. Due to the fact that there is no consensus on the choice of values for these parameters, in the article they are studied on simulated fractal time series with lengths of 600-3000 points. The values of ApEn, SampEn and the value of the Hurst exponent were found to be negatively correlated, and the predictability was positively related to the Hurst exponent. Both entropy-based methods and the Hurst exponent were used to study the dynamics of the behavior of real-time series related to heart rate intervals (RR interval series) to extract useful information related to the influence of the age of the subjects. The results show that the values of ApEn and SampEn are higher for young subjects than for adults, therefore the RR time series of young subjects is more complex than the time series of adult subjects. The value of the Hurst exponent of young subjects was found to be lower than that of adult subjects, therefore the time series of adult subjects have a higher degree of self-similarity. The results reported in this study may be useful in analysing cardiac data to extract useful information in clinical decision making.
No takes yet. Share an insight, caveat, or question.
Еvgeniya Gospodinova (2022) studied Heart rate intervals (RR interval series). Young age vs. Adult age was evaluated on Approximate entropy (ApEn), sample entropy (SampEn), and Hurst exponent. Young subjects exhibited higher approximate and sample entropy and lower Hurst exponents in their RR interval time series compared to adult subjects, indicating greater complexity.
Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context: