Key result
Extensive fibrofatty infiltration of the left ventricle without right ventricular involvement caused sudden cardiac death in two young men.
Highlights that extensive fibrofatty infiltration can occur primarily in the left ventricle and present as sudden cardiac death in young individuals.
Warrants consideration in young SCD autopsies; leaves open whether left-dominant fibrofatty replacement represents a novel entity.
Replacement of the myocardium by fibrous and adipose tissue is well documented in the right ventricle, but has been rarely described in the left ventricle. We present two cases of extensive fibrofatty infiltration of the left ventricle without significant right ventricular involvement in young men whose presenting symptom was sudden death.
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Collett et al. (1994) studied this question. Extensive fibrofatty infiltration of the left ventricle without right ventricular involvement caused sudden cardiac death in two young men.
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