Key result
Circadian rhythm disruption linked to higher risk of hypertension, atherosclerosis, heart failure, and arrhythmias.
Why the study?
Disruptions of the circadian clock can elevate the risk of cardiovascular diseases, warranting an examination of circadian regulation from molecular mechanisms to clinical implications.
Design
Review
Authors
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May inform circadian-aware CV risk assessment; leaves open interventional trials to guide therapy.
Circadian disruption contributes to cardiovascular disease risk, highlighting the potential of chronotherapy, time-restricted eating, and physical activity in cardiovascular prevention and management.
Malhan et al. (2026) conducted a review in Cardiovascular diseases. Circadian rhythm disruption was evaluated. Circadian rhythm disruption significantly elevates the risk of cardiovascular diseases, including hypertension, atherosclerosis, heart failure, and arrhythmias.